Cleveland Clinic Cancer Advances

Young-onset colorectal cancer is becoming more common, and the microbiome could be playing a role in the increase of cases. Alok Khorana, MD, Director of the Gastrointestinal Malignancies Program at Cleveland Clinic Cancer Institute, joins the Cancer Advances Podcast to discuss this issue. Listen as Dr. Khorana highlights his research on the link between changes in the microbiome a

The Cancer Advances podcast is joined by colorectal surgeons, I. Emre Gorgun, MD, Vice Chair of the Department of Colorectal Surgery, and Joshua Sommovilla, MD, Director of the Colon Cancer Tumor Board, to talk about organ preservation in rectal cancer treatment. Listen as they discuss the rising use of neoadjuvant therapy to shrink tumors before surgery, endoluminal procedures, an

Shilpa Gupta, MD, Director of the Genitourinary Oncology Program at Cleveland Clinic Cancer Institute, provides an overview of the clinical trial of enfortumab vedotin and pembrolizumab in untreated advanced urothelial cancer. Listen as Dr. Gupta talks about the exciting results of the trial, which showed that the combination therapy was effective for both cisplatin-eligible and ci

Anjali Advani, MD, Director of the Inpatient Leukemia Unit at Cleveland Clinic, joins the Cancer Advances Podcast to talk about the innovations in acute lymphoblastic leukemia (ALL). While chemotherapy has traditionally been the go-to treatment, advancements like blinatumomab and CAR-T cell therapy are reshaping care. Listen as Dr. Advani discusses the challenges and considerations

Halle Moore, MD, Director of Breast Medical Oncology at Cleveland Clinic, joins the Cancer Advances Podcast to explore the safety of pregnancy after breast cancer with BRCA mutations. In the episode, Dr. Moore emphasizes the importance of early conversations regarding reproductive goals and available fertility preservation strategies for breast cancer patients while maintaining an

Hematology oncologist, Allison Winter, MD, joins the Cancer Advances podcast to discuss the latest innovations in treating chronic lymphocytic leukemia (CLL). Listen as she explains how the treatment for CLL has evolved over the past decade, with a shift towards using novel therapies such as BTK inhibitors and venetoclax, as well as the concept of time-limited therapy. Dr. Winter a

Alison Ibsen, Senior Director for Cancer Programming, joins the Cancer Advances Podcast to talk about the role of cancer programming to enhance cancer patient care. Cancer programming brings together various experts involved in the treatment of a specific cancer to promote multidisciplinary care to help improve outcomes. Listen as Alison elaborates on the program development, its e

Michael Valente, DO, Program Director for the Colorectal Surgery Residency Program, and Director of the Peritoneal Surface Malignancy Program & Center for Metastatic Colorectal Cancer at Cleveland Clinic, joins the Cancer Advances Podcast to discuss advances in stage 4 colon cancer treatment. Listen as Dr. Valente highlights the significant improvements in outcomes for late

The Cancer Advances podcast is joined by surgeon, Federico Aucejo, MD, Director of the Liver Tumor Clinic, and medical GI oncologist, Bassam Estfan, MD, Co-Director of the Liver Tumor Program, to discuss the use of ctDNA screening in colorectal cancer with liver metastases. Tune in to learn about the current state of disease management and the potential of ctDNA testing to guide tr

Michelle Kuznicki, MD, a gynecologic oncologist, joins the Cancer Advances podcast to talk about fertility-sparing surgery for early-stage cervical cancer. Drawing from her systematic review of oncologic and pregnancy outcomes associated with various surgical techniques, Dr. Kuznicki talks about the shift towards less invasive procedures, highlighting the importance of aligning sur